Platform architecture
Laboratory orchestration across equipment and software.
BioSphereer connects existing infrastructure through a modular integration architecture while preserving controlled execution, permissions, lineage, and complete auditability.
Laboratory orchestration
Connect research intelligence to controlled execution.
Approved research workflows become structured laboratory operations spanning plasmid assembly, robotic transfers, probe handling, cultivation, analysis, storage, and complete sample lineage.
Existing instruments
DNA assembly stations, liquid handlers, robotic workcells, incubators, readers, sequencers, storage, and sensors.
Modular connectors
REST, vendor SDKs, OPC UA, SiLA 2, files, queues, and adapter interfaces.
Live Laboratory
Campaign progress, device state, sample location, transfer queues, probe status, anomalies, alerts, and approvals.
Automated production line
From an approved construct to a measured yeast culture.
FORGE compiles operations, SENTINEL guards the execution boundary, ORBIT schedules machinery and transfers, PULSE watches live state, and TRACE preserves every material and instrument handoff.
- Plasmid build plan
Construct design
Compile an approved construct and protocol against validated capabilities.
FORGE · SENTINEL - Plasmid engineering station
DNA assembly
Execute the governed plasmid build and preserve material identity and lineage.
FORGE · ORBIT · TRACE - Robotic transport workcell
Sample transfer
Route closed, barcoded labware through authenticated instrument handoffs.
ORBIT · PULSE · TRACE - Sequencer · plate reader
Strain verification
Connect sequence and assay evidence to the candidate yeast strain.
PRISM · TRACE - Bioreactor · probe arm
Cultivation control
Run expression conditions with monitored probe placement and process state.
FORGE · ORBIT · PULSE - Reader · chromatography
Analysis
Measure expression and quality while checking analytical integrity.
PRISM · PULSE - Robotic sample storage
Tracked storage
Preserve location, retention state, and authorized sample retrieval.
ORBIT · TRACE
Connected machinery
One governed control plane across laboratory equipment.
Each approved operation is matched to a validated device capability, scheduled with samples and resources, monitored through telemetry, and preserved in the campaign’s provenance record.
DNA Assembly & Plasmid Engineering Station
Translates approved construct designs into traceable plasmid-build runs, coordinating assembly setup, cleanup, and the verification handoff.
Robotic liquid handler
Maps validated pipetting operations to plates, reagents, samples, and scheduled deck positions.
Robotic sample-transfer system
Routes barcoded plates, tubes, and racks between workcells while preserving transfer telemetry, location, and chain of custody.
Incubator shaker
Maintains scheduled yeast-culture conditions while telemetry is monitored for deviations.
Parallel bioreactor array
Runs controlled expression conditions in parallel and streams process state into the campaign record.
Robotic probe-handling arm
Selects, positions, exchanges, and docks approved calibrated probes while their tool state and process telemetry remain monitored.
Multimode plate reader
Ingests assay measurements, applies quality control, and links every output to its sample lineage.
Benchtop sequencer
Captures sequence-derived evidence and preserves the instrument, run, and dataset versions used.
Robotic sample storage
Maintains location, chain of custody, retention state, and authorized retrieval for every sample.
Analytical chromatography
Measures purification and quality outcomes while monitoring instrument health and analytical integrity.
Sample journey
Every sample remains traceable across its complete lifecycle.
Unique identity, lineage, location, device history, measurements, chain of custody, retention, and disposition remain connected to the research campaign.
Research intelligence
Every experiment becomes part of the platform’s research memory.
BioSphereer does more than store experiments. It structures how goals, evidence, samples, device states, results, and decisions connect to measured outcomes.
Evidence Graph
Trace each claim to supporting and contradictory evidence, quality, confidence, source, recency, and review state.
Research lineage
Follow every transformation from objective to experiment, measurement, result, decision, and next iteration.
Governance by design
Separate predictions from measurements while preserving approvals, versions, permissions, and replayable history.
Layered system
A modular operating system for biological research.
Each layer has a clear responsibility and interface.